Human SCRG1 activation kit by CRISPRa

CAT#: GA107808

SCRG1 CRISPRa kit - CRISPR gene activation of human stimulator of chondrogenesis 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCRG1
• Locus ID: 11341
• Kit Components:

  GA107808G1, SCRG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107808G2, SCRG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107808G3, SCRG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329597, NM_007281
• Synonyms: SCRG-1
• Summary: Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. In addition, the encoded protein can interact with bone marrow stromal cell antigen 1 (BST1) to enhance the differentiation potentials of human mesenchymal stem cells during tissue and bone regeneration. [provided by RefSeq, Jul 2016]