Human MAPRE1 activation kit by CRISPRa

CAT#: GA107912

MAPRE1 CRISPRa kit - CRISPR gene activation of human microtubule associated protein RP/EB family member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAPRE1
• Locus ID: 22919
• Kit Components:

  GA107912G1, MAPRE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107912G2, MAPRE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107912G3, MAPRE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012325
• Synonyms: EB1
• Summary: The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]