Human WDFY3 activation kit by CRISPRa

CAT#: GA107961

WDFY3 CRISPRa kit - CRISPR gene activation of human WD repeat and FYVE domain containing 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WDFY3
• Locus ID: 23001
• Kit Components:

  GA107961G1, WDFY3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107961G2, WDFY3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107961G3, WDFY3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014991, NM_178583, NM_178585
• Synonyms: ALFY; ZFYVE25
• Summary: This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]