Human EXOC7 activation kit by CRISPRa

CAT#: GA108175

EXOC7 CRISPRa kit - CRISPR gene activation of human exocyst complex component 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXOC7
• Locus ID: 23265
• Kit Components:

  GA108175G1, EXOC7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108175G2, EXOC7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108175G3, EXOC7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001013839, NM_001145296, NM_001145297, NM_001145298, NM_001145299, NM_001282313, NM_001282314, NM_015219, NR_028133
• Synonyms: 2-5-3p; EX070; EXO70; Exo70p; EXOC1; YJL085W
• Summary: The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]