Human USP24 activation kit by CRISPRa

CAT#: GA108246

USP24 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP24
• Locus ID: 23358
• Kit Components:

  GA108246G1, USP24 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108246G2, USP24 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108246G3, USP24 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015306
• Synonyms: FLJ31309; KIAA1057
• Summary: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]). [supplied by OMIM, Mar 2008]