Human DDAH2 activation kit by CRISPRa

CAT#: GA108403

DDAH2 CRISPRa kit - CRISPR gene activation of human dimethylarginine dimethylaminohydrolase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DDAH2
• Locus ID: 23564
• Kit Components:

  GA108403G1, DDAH2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108403G2, DDAH2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108403G3, DDAH2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303007, NM_001303008, NM_013974
• Synonyms: DDAH; DDAHII; G6a; HEL-S-277; NG30
• Summary: This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014]