Human NUP62 activation kit by CRISPRa

CAT#: GA108450

NUP62 CRISPRa kit - CRISPR gene activation of human nucleoporin 62

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUP62
• Locus ID: 23636
• Kit Components:

  GA108450G1, NUP62 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108450G2, NUP62 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108450G3, NUP62 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001193357, NM_012346, NM_016553, NM_153718, NM_153719
• Synonyms: IBSN; p62; SNDI
• Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008]