Human TIAM2 activation kit by CRISPRa

CAT#: GA108806

TIAM2 CRISPRa kit - CRISPR gene activation of human T cell lymphoma invasion and metastasis 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TIAM2
• Locus ID: 26230
• Kit Components:

  GA108806G1, TIAM2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108806G2, TIAM2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108806G3, TIAM2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010927, NM_012454
• Synonyms: STEF; TIAM-2
• Summary: This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]