Human Nucleostemin (GNL3) activation kit by CRISPRa

CAT#: GA108861

GNL3 CRISPRa kit - CRISPR gene activation of human G protein nucleolar 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNL3
• Locus ID: 26354
• Kit Components:

  GA108861G1, GNL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108861G2, GNL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108861G3, GNL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014366, NM_206825, NM_206826
• Synonyms: C77032; E2IG3; NNP47; NS
• Summary: The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]