Human TIMM8B activation kit by CRISPRa

CAT#: GA108888

TIMM8B CRISPRa kit - CRISPR gene activation of human translocase of inner mitochondrial membrane 8 homolog B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TIMM8B
• Locus ID: 26521
• Kit Components:

  GA108888G1, TIMM8B gRNA vector 1 in pCas-Guide-CRISPRa

  GA108888G2, TIMM8B gRNA vector 2 in pCas-Guide-CRISPRa

  GA108888G3, TIMM8B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012459, NR_028383, NR_160400
• Synonyms: DDP2; TIM8B
• Summary: This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma. [provided by RefSeq, Aug 2009]