Human HIV TAT specific factor 1 (HTATSF1) activation kit by CRISPRa

CAT#: GA109129

HTATSF1 CRISPRa kit - CRISPR gene activation of human HIV-1 Tat specific factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HTATSF1
• Locus ID: 27336
• Kit Components:

  GA109129G1, HTATSF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109129G2, HTATSF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109129G3, HTATSF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163280, NM_014500
• Synonyms: dJ196E23.2; TAT-SF1; TATSF1
• Summary: The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]