Human DNA Polymerase lambda (POLL) activation kit by CRISPRa

CAT#: GA109135

POLL CRISPRa kit - CRISPR gene activation of human DNA polymerase lambda

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLL
• Locus ID: 27343
• Kit Components:

  GA109135G1, POLL gRNA vector 1 in pCas-Guide-CRISPRa

  GA109135G2, POLL gRNA vector 2 in pCas-Guide-CRISPRa

  GA109135G3, POLL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001174084, NM_001174085, NM_013274, NR_033406, NM_001308382
• Synonyms: BETAN; POLKAPPA
• Summary: This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]