Human EEF2K activation kit by CRISPRa

CAT#: GA109302

EEF2K CRISPRa kit - CRISPR gene activation of human eukaryotic elongation factor 2 kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EEF2K
• Locus ID: 29904
• Kit Components:

  GA109302G1, EEF2K gRNA vector 1 in pCas-Guide-CRISPRa

  GA109302G2, EEF2K gRNA vector 2 in pCas-Guide-CRISPRa

  GA109302G3, EEF2K gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013302
• Synonyms: eEF-2K; HSU93850
• Summary: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]