Human Adiponectin Receptor 1 (ADIPOR1) activation kit by CRISPRa

CAT#: GA109558

ADIPOR1 CRISPRa kit - CRISPR gene activation of human adiponectin receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADIPOR1
• Locus ID: 51094
• Kit Components:

  GA109558G1, ADIPOR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109558G2, ADIPOR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109558G3, ADIPOR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127687, NM_001290553, NM_001290557, NM_001290629, NM_015999, NR_046083
• Synonyms: ACDCR1; CGI-45; CGI45; FLJ25385; FLJ42464; PAQR1; TESBP1A
• Summary: This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]