Human RBJ (DNAJC27) activation kit by CRISPRa

CAT#: GA109697

DNAJC27 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member C27

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJC27
• Locus ID: 51277
• Kit Components:

  GA109697G1, DNAJC27 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109697G2, DNAJC27 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109697G3, DNAJC27 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198559, NM_016544
• Synonyms: RabJS; RBJ
• Summary: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. [UniProtKB/Swiss-Prot Function]