Human AHSP activation kit by CRISPRa

CAT#: GA109744

AHSP CRISPRa kit - CRISPR gene activation of human alpha hemoglobin stabilizing protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AHSP
• Locus ID: 51327
• Kit Components:

  GA109744G1, AHSP gRNA vector 1 in pCas-Guide-CRISPRa

  GA109744G2, AHSP gRNA vector 2 in pCas-Guide-CRISPRa

  GA109744G3, AHSP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318221, NM_001318222, NM_016633
• Synonyms: EDRF; ERAF
• Summary: This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]