Human Angiopoietin 4 (ANGPT4) activation kit by CRISPRa

CAT#: GA109776

ANGPT4 CRISPRa kit - CRISPR gene activation of human angiopoietin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANGPT4
• Locus ID: 51378
• Kit Components:

  GA109776G1, ANGPT4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109776G2, ANGPT4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109776G3, ANGPT4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001322809, NM_015985
• Synonyms: ANG3; ANG4
• Summary: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008]