Human AMOTL2 activation kit by CRISPRa

CAT#: GA109795

AMOTL2 CRISPRa kit - CRISPR gene activation of human angiomotin like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMOTL2
• Locus ID: 51421
• Kit Components:

  GA109795G1, AMOTL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109795G2, AMOTL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109795G3, AMOTL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278683, NM_001278685, NM_016201, NM_001363943
• Synonyms: LCCP
• Summary: Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]