Human CNNM2 activation kit by CRISPRa

CAT#: GA110272

CNNM2 CRISPRa kit - CRISPR gene activation of human cyclin and CBS domain divalent metal cation transport mediator 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CNNM2
• Locus ID: 54805
• Kit Components:

  GA110272G1, CNNM2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110272G2, CNNM2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110272G3, CNNM2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017649, NM_199076, NM_199077
• Synonyms: ACDP2; HOMG6; HOMGSMR
• Summary: This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]