Human MS4A12 activation kit by CRISPRa

CAT#: GA110319

MS4A12 CRISPRa kit - CRISPR gene activation of human membrane spanning 4-domains A12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MS4A12
• Locus ID: 54860
• Kit Components:

  GA110319G1, MS4A12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110319G2, MS4A12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110319G3, MS4A12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164470, NM_017716
• Synonyms: Ms4a10
• Summary: The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]