Human TMEM16K (ANO10) activation kit by CRISPRa

CAT#: GA110537

ANO10 CRISPRa kit - CRISPR gene activation of human anoctamin 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANO10
• Locus ID: 55129
• Kit Components:

  GA110537G1, ANO10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110537G2, ANO10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110537G3, ANO10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204831, NM_001204832, NM_001204833, NM_001204834, NM_018075, NM_001346463, NM_001346464, NM_001346465, NM_001346466, NM_001346467, NM_001346468, NM_001346469
• Synonyms: SCAR10; TMEM16K
• Summary: The transmembrane protein encoded by this gene belongs to the anoctamin family of calcium-activated chloride channels, also known as the transmembrane 16 family. The encoded protein contains eight transmembrane domains with cytosolic N- and C-termini. Defects in this gene may cause autosomal recessive spinocerebellar ataxia-10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]