Human POMGNT1 activation kit by CRISPRa

CAT#: GA110833

POMGNT1 CRISPRa kit - CRISPR gene activation of human protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POMGNT1
• Locus ID: 55624
• Kit Components:

  GA110833G1, POMGNT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110833G2, POMGNT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110833G3, POMGNT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243766, NM_001290129, NM_001290130, NM_017739, NR_024332
• Synonyms: gnT-I.2; GNTI.2; GnT I.2; LGMD2O; MEB; MGAT1.2; RP76
• Summary: This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]