Human FLVCR2 activation kit by CRISPRa

CAT#: GA110847

FLVCR2 CRISPRa kit - CRISPR gene activation of human feline leukemia virus subgroup C cellular receptor family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FLVCR2
• Locus ID: 55640
• Kit Components:

  GA110847G1, FLVCR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110847G2, FLVCR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110847G3, FLVCR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195283, NM_017791
• Synonyms: C14orf58; CCT; EPV; FLVCRL14q; MFSD7C; PVHH
• Summary: This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]