Human TMEM165 activation kit by CRISPRa

CAT#: GA111024

TMEM165 CRISPRa kit - CRISPR gene activation of human transmembrane protein 165

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMEM165
• Locus ID: 55858
• Kit Components:

  GA111024G1, TMEM165 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111024G2, TMEM165 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111024G3, TMEM165 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018475, NR_073070
• Synonyms: CDG2K; FT27; GDT1; TMPT27; TPARL
• Summary: This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]