Human PBK activation kit by CRISPRa

CAT#: GA111034

PBK CRISPRa kit - CRISPR gene activation of human PDZ binding kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PBK
• Locus ID: 55872
• Kit Components:

  GA111034G1, PBK gRNA vector 1 in pCas-Guide-CRISPRa

  GA111034G2, PBK gRNA vector 2 in pCas-Guide-CRISPRa

  GA111034G3, PBK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278945, NM_018492, NM_001363040
• Synonyms: CT84; HEL164; Nori-3; SPK; TOPK
• Summary: This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]