Human PREX1 activation kit by CRISPRa

CAT#: GA111607

PREX1 CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PREX1
• Locus ID: 57580
• Kit Components:

  GA111607G1, PREX1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111607G2, PREX1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111607G3, PREX1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020820
• Synonyms: P-REX1
• Summary: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]