Human ARHGAP21 activation kit by CRISPRa

CAT#: GA111610

ARHGAP21 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 21

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARHGAP21
• Locus ID: 57584
• Kit Components:

  GA111610G1, ARHGAP21 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111610G2, ARHGAP21 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111610G3, ARHGAP21 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020824, NM_001367447, NM_001367448, NM_001367453, NM_001367454, NR_160022, NR_160024, NM_001367449, NM_001367450, NM_001367451, NM_001367452, NM_001367455, NR_160021, NR_160023, NR_160025
• Synonyms: ARHGAP10
• Summary: ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]). [supplied by OMIM, Mar 2008]