Human GPAM activation kit by CRISPRa

CAT#: GA111677

GPAM CRISPRa kit - CRISPR gene activation of human glycerol-3-phosphate acyltransferase, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPAM
• Locus ID: 57678
• Kit Components:

  GA111677G1, GPAM gRNA vector 1 in pCas-Guide-CRISPRa

  GA111677G2, GPAM gRNA vector 2 in pCas-Guide-CRISPRa

  GA111677G3, GPAM gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244949, NM_020918
• Synonyms: GPAT; GPAT1
• Summary: This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]