Human PAG608 (ZMAT3) activation kit by CRISPRa

CAT#: GA112054

ZMAT3 CRISPRa kit - CRISPR gene activation of human zinc finger matrin-type 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZMAT3
• Locus ID: 64393
• Kit Components:

  GA112054G1, ZMAT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112054G2, ZMAT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112054G3, ZMAT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022470, NM_152240
• Synonyms: PAG608; WIG-1; WIG1
• Summary: This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008]