Human IL17E (IL25) activation kit by CRISPRa

CAT#: GA112161

IL25 CRISPRa kit - CRISPR gene activation of human interleukin 25

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL25
• Locus ID: 64806
• Kit Components:

  GA112161G1, IL25 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112161G2, IL25 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112161G3, IL25 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022789, NM_172314
• Synonyms: IL17E
• Summary: The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]