Human Apolipoprotein O (APOO) activation kit by CRISPRa

CAT#: GA112376

APOO CRISPRa kit - CRISPR gene activation of human apolipoprotein O

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOO
• Locus ID: 79135
• Kit Components:

  GA112376G1, APOO gRNA vector 1 in pCas-Guide-CRISPRa

  GA112376G2, APOO gRNA vector 2 in pCas-Guide-CRISPRa

  GA112376G3, APOO gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024122, NR_026545
• Synonyms: FAM121B; Mic23; MIC26; My025
• Summary: This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16. [provided by RefSeq, Sep 2009]