Human QTRTD1 (QTRT2) activation kit by CRISPRa

CAT#: GA112551

QTRT2 CRISPRa kit - CRISPR gene activation of human queuine tRNA-ribosyltransferase accessory subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: QTRT2
• Locus ID: 79691
• Kit Components:

  GA112551G1, QTRT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112551G2, QTRT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112551G3, QTRT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256835, NM_001256836, NM_001256837, NM_024638
• Summary: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]