Human ARMC5 activation kit by CRISPRa

CAT#: GA112633

ARMC5 CRISPRa kit - CRISPR gene activation of human armadillo repeat containing 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARMC5
• Locus ID: 79798
• Kit Components:

  GA112633G1, ARMC5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112633G2, ARMC5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112633G3, ARMC5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001105247, NM_001288767, NM_001301820, NM_024742
• Synonyms: AIMAH2
• Summary: This gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. The ARM repeat is a tandemly repeated sequence motif with approximately 40 amino acid long. This repeat is implicated in mediating protein-protein interactions. The encoded protein contains seven ARM repeats. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]