Human EDC3 activation kit by CRISPRa

CAT#: GA112841

EDC3 CRISPRa kit - CRISPR gene activation of human enhancer of mRNA decapping 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EDC3
• Locus ID: 80153
• Kit Components:

  GA112841G1, EDC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112841G2, EDC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112841G3, EDC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142443, NM_001142444, NM_025083, NM_001351378, NM_001351379
• Synonyms: LSM16; YJDC; YJEFN2
• Summary: This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]