Human RAB11FIP1 activation kit by CRISPRa

CAT#: GA112879

RAB11FIP1 CRISPRa kit - CRISPR gene activation of human RAB11 family interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAB11FIP1
• Locus ID: 80223
• Kit Components:

  GA112879G1, RAB11FIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112879G2, RAB11FIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112879G3, RAB11FIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002233, NM_001002814, NM_025151
• Synonyms: DKFZp686E2214; FLJ22524; FLJ22622; MGC78448; NOEL1A; rab11-FIP1; RCP
• Summary: This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]