Human PAAF1 activation kit by CRISPRa

CAT#: GA112881

PAAF1 CRISPRa kit - CRISPR gene activation of human proteasomal ATPase associated factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAAF1
• Locus ID: 80227
• Kit Components:

  GA112881G1, PAAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112881G2, PAAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112881G3, PAAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001267803, NM_001267804, NM_001267805, NM_001267806, NM_025155, NM_001363556
• Synonyms: PAAF; Rpn14; WDR71
• Summary: This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]