Human LC3B (MAP1LC3B) activation kit by CRISPRa

CAT#: GA113105

MAP1LC3B CRISPRa kit - CRISPR gene activation of human microtubule associated protein 1 light chain 3 beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAP1LC3B
• Locus ID: 81631
• Kit Components:

  GA113105G1, MAP1LC3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA113105G2, MAP1LC3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA113105G3, MAP1LC3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022818
• Synonyms: ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a
• Summary: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]