Human KCNK16 activation kit by CRISPRa

CAT#: GA113268

KCNK16 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK16
• Locus ID: 83795
• Kit Components:

  GA113268G1, KCNK16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113268G2, KCNK16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113268G3, KCNK16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135105, NM_001135106, NM_001135107, NM_032115, NM_001363784
• Synonyms: K2p16.1; TALK-1; TALK1
• Summary: The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]