Human MAP1LC3A activation kit by CRISPRa

CAT#: GA113597

MAP1LC3A CRISPRa kit - CRISPR gene activation of human microtubule associated protein 1 light chain 3 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAP1LC3A
• Locus ID: 84557
• Kit Components:

  GA113597G1, MAP1LC3A gRNA vector 1 in pCas-Guide-CRISPRa

  GA113597G2, MAP1LC3A gRNA vector 2 in pCas-Guide-CRISPRa

  GA113597G3, MAP1LC3A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032514, NM_181509
• Synonyms: ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3
• Summary: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]