Human MURF1 (TRIM63) activation kit by CRISPRa

CAT#: GA113647

TRIM63 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 63

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIM63
• Locus ID: 84676
• Kit Components:

  GA113647G1, TRIM63 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113647G2, TRIM63 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113647G3, TRIM63 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032588
• Synonyms: IRF; MURF1; MURF2; RNF28; SMRZ
• Summary: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]