Human CREB3L3 activation kit by CRISPRa

CAT#: GA113664

CREB3L3 CRISPRa kit - CRISPR gene activation of human cAMP responsive element binding protein 3 like 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CREB3L3
• Locus ID: 84699
• Kit Components:

  GA113664G1, CREB3L3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113664G2, CREB3L3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113664G3, CREB3L3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271995, NM_001271996, NM_001271997, NM_032607
• Synonyms: CREB-H; CREBH; HYST1481
• Summary: This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]