Human USP45 activation kit by CRISPRa

CAT#: GA113829

USP45 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 45

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP45
• Locus ID: 85015
• Kit Components:

  GA113829G1, USP45 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113829G2, USP45 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113829G3, USP45 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080481, NM_001346021, NM_001346022, NM_001346023, NM_001346024, NM_001346025, NM_001346026, NM_001346027, NM_001346028, NM_001346029, NM_001346030, NM_001346033, NM_032929, NR_144344, NR_144345, NR_144346, NR_144347, NR_144348
• Synonyms: MGC14793
• Summary: The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]