Human NKD2 activation kit by CRISPRa

CAT#: GA113873

NKD2 CRISPRa kit - CRISPR gene activation of human NKD inhibitor of WNT signaling pathway 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NKD2
• Locus ID: 85409
• Kit Components:

  GA113873G1, NKD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113873G2, NKD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113873G3, NKD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271082, NM_033120
• Synonyms: Naked2
• Summary: This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]