Human Neuron navigator 1 (NAV1) activation kit by CRISPRa

CAT#: GA113932

NAV1 CRISPRa kit - CRISPR gene activation of human neuron navigator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAV1
• Locus ID: 89796
• Kit Components:

  GA113932G1, NAV1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113932G2, NAV1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113932G3, NAV1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167738, NM_020443
• Synonyms: POMFIL3; STEERIN1; UNC53H1
• Summary: This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]