Human Mimitin (NDUFAF2) activation kit by CRISPRa

CAT#: GA114168

NDUFAF2 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase complex assembly factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFAF2
• Locus ID: 91942
• Kit Components:

  GA114168G1, NDUFAF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114168G2, NDUFAF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114168G3, NDUFAF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_174889
• Synonyms: B17.2L; mimitin; MMTN; NDUFA12L
• Summary: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. [provided by RefSeq, Jul 2008]