Human CMTM7 activation kit by CRISPRa

CAT#: GA114361

CMTM7 CRISPRa kit - CRISPR gene activation of human CKLF like MARVEL transmembrane domain containing 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CMTM7
• Locus ID: 112616
• Kit Components:

  GA114361G1, CMTM7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114361G2, CMTM7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114361G3, CMTM7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138410, NM_181472
• Synonyms: CKLFSF7
• Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]