Human SH2D1B activation kit by CRISPRa

CAT#: GA114630

SH2D1B CRISPRa kit - CRISPR gene activation of human SH2 domain containing 1B


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol SH2D1B
Locus ID 117157
Kit Components

GA114630G1, SH2D1B gRNA vector 1 in pCas-Guide-CRISPRa

GA114630G2, SH2D1B gRNA vector 2 in pCas-Guide-CRISPRa

GA114630G3, SH2D1B gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_053282
Synonyms EAT2
Summary By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.