Human AP1S3 activation kit by CRISPRa
CAT#: GA115108
AP1S3 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 1 subunit sigma 3
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | AP1S3 |
Locus ID | 130340 |
Kit Components | GA115108G1, AP1S3 gRNA vector 1 in pCas-Guide-CRISPRa GA115108G2, AP1S3 gRNA vector 2 in pCas-Guide-CRISPRa GA115108G3, AP1S3 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001039569, NM_178814, NR_110905, NR_110906 |
Synonyms | PSORS15 |
Summary | This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN420329 | AP1S3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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