Human Sphingosine 1 phosphate phosphatase 2 (SGPP2) activation kit by CRISPRa

CAT#: GA115110

SGPP2 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate phosphatase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SGPP2
• Locus ID: 130367
• Kit Components:

  GA115110G1, SGPP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115110G2, SGPP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115110G3, SGPP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320833, NM_001320834, NM_152386
• Synonyms: SPP2; SPPase2
• Summary: The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]