Human KCNU1 activation kit by CRISPRa

CAT#: GA115937

KCNU1 CRISPRa kit - CRISPR gene activation of human potassium calcium-activated channel subfamily U member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNU1
• Locus ID: 157855
• Kit Components:

  GA115937G1, KCNU1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115937G2, KCNU1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115937G3, KCNU1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031836, NR_134267
• Synonyms: KCa5; KCa5.1; Kcnma3; KCNMC1; Slo3
• Summary: This gene encodes a member of the potassium channel family of proteins. The encoded voltage-gated ion channel allows the outward flow of potassium ions during plasma membrane hyperpolarization in sperm. Opening of this channel may be regulated by calcium ion levels. Homozygous knockout mice that lack the related mouse gene exhibit male sterility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]